Any wound, any time.

Transforming healing with bioactive science

You know what it takes to efficiently heal a wound. That’s why our advanced wound care portfolio begins with essential bioburden and biofilm control and extends to breakthrough regenerative medicine.

Because time doesn’t heal all wounds, we don’t stop when wounds stall. From acute to chronic, from start to finish, wounds require a rapid response. Our specialized bioactive and regenerative wound care products help you heal without hesitation.

Puraply™ Antimicrobial

PuraPly Antimicrobial is the first purified native collagen matrix with polyhexamethylene biguanide (PHMB), a broad-spectrum, noncytotoxic antimicrobial. PuraPly Antimicrobial works to reduce bioburden and inhibit biofilm formation and support healing across a wide variety of wound types, regardless of severity or duration.1

Dermagraft®

Dermagraft is a cryopreserved human fibroblast-derived dermal substitute composed of human fibroblasts, extra cellular matrix, and a bioabsorbable scaffold. Dermagraft is indicated for use in the treatment of full-thickness diabetic foot ulcers (DFUs) greater than 6 weeks duration, which extend through the dermis, but without tendon, muscle, joint capsule, or bone exposure.2

Apligraf®

Apligraf is a bilayered, living cell-based product containing living human keratinocytes and fibroblasts embedded in a type 1 collagen matrix. Apligraf is approved for the treatment of noninfected partial- and/or full-thickness venous leg ulcers (VLUs) of greater than 1 month duration and of full-thickness neuropathic foot ulcers of greater than 3 weeks duration without tendon, muscle, capsule, or bone exposure.3

Affinity®

Affinity is the only fresh amniotic membrane (not dehydrated, not frozen) consisting of an epithelial layer, basement membrane, stromal layer, and spongy layer. The proprietary AlloFresh™ process allows for the hypothermic storage of the amniotic tissue in its fresh state, retaining its native tissue benefits, structural integrity, and viability. Affinity can be applied to a variety of partial- and full-thickness, acute, and chronic wounds.4

NuShield®

NuShield is a dehydrated placental allograft including the amnion and chorion with the spongy layer intact. The proprietary BioLoc™ process allows NuShield to be stored at room temperature, and it provides excellent strength, flexibility, and handling characteristics while preserving the native protein content. NuShield can be applied to a variety of partial- and full-thickness, acute, and chronic wounds.5

Product Support

Organogenesis provides a wide range of programs and services to assist you and your facility at every step.

  • Customer care center
  • Reimbursement support center
  • Charitable assistance programs
  • Medical and technical support

Call 1-888-432-5232

Our expertly trained support specialists are available from 8:00 AM to 8:00 PM ET.

PuraPly Antimicrobial is the first purified native collagen matrix with polyhexamethylene biguanide (PHMB), a broad-spectrum, noncytotoxic antimicrobial. PuraPly Antimicrobial works to reduce bioburden and inhibit biofilm formation and support healing across a wide variety of wound types, regardless of severity or duration.1

Dermagraft is a cryopreserved human fibroblast-derived dermal substitute composed of human fibroblasts, extra cellular matrix, and a bioabsorbable scaffold. Dermagraft is indicated for use in the treatment of full-thickness diabetic foot ulcers (DFUs) greater than 6 weeks duration, which extend through the dermis, but without tendon, muscle, joint capsule, or bone exposure.2

Apligraf is a bilayered, living cell-based product containing living human keratinocytes and fibroblasts embedded in a type 1 collagen matrix. Apligraf is approved for the treatment of noninfected partial- and/or full-thickness venous leg ulcers (VLUs) of greater than 1 month duration and of full-thickness neuropathic foot ulcers of greater than 3 weeks duration without tendon, muscle, capsule, or bone exposure.3

Affinity is the only fresh amniotic membrane (not dehydrated, not frozen) consisting of an epithelial layer, basement membrane, stromal layer, and spongy layer. The proprietary AlloFresh™ process allows for the hypothermic storage of the amniotic tissue in its fresh state, retaining its native tissue benefits, structural integrity, and viability. Affinity can be applied to a variety of partial- and full-thickness, acute, and chronic wounds.4

NuShield is a dehydrated placental allograft including the amnion and chorion with the spongy layer intact. The proprietary BioLoc™ process allows NuShield to be stored at room temperature, and it provides excellent strength, flexibility, and handling characteristics while preserving the native protein content. NuShield can be applied to a variety of partial- and full-thickness, acute, and chronic wounds.5

Organogenesis provides a wide range of programs and services to assist you and your facility at every step.

  • Customer care center
  • Reimbursement support center
  • Charitable assistance programs
  • Medical and technical support

Call 1-888-432-5232

Our expertly trained support specialists are available from 8:00 AM to 8:00 PM ET.

Right from the start, right to the finish.

Our advanced wound care portfolio keeps wounds on a healing trajectory.

Learn How

References: 1. PuraPly™ Antimicrobial [package insert]. Canton, MA: Organogenesis, Inc; 2015. 2. Dermagraft® [package insert]. Canton, MA: Organogenesis Inc.; 2010. 3. Apligraf® [package insert]. Canton, MA: Organogenesis Inc.; 2010. 4. Affinity® [package insert]. Birmingham, AL: NuTech Medical, a Division of Organogenesis Inc; 2017. 5. NuShield® [package insert]. Birmingham, AL: NuTech Medical, a Division of Organogenesis Inc; 2017.